Short-term tests for environmentally induced chronic health effects
Read Online

Short-term tests for environmentally induced chronic health effects

  • 633 Want to read
  • ·
  • 19 Currently reading

Published by Office of Research and Development, U.S. Environmental Protection Agency, Center for Environmental Research Information, [distributor] in Washington, D.C, Cincinnati, OH .
Written in English


  • Environmental toxicology -- United States,
  • Biological assay,
  • Environmental chemistry -- United States

Book details:

Edition Notes

StatementAvril D. Woodhead, editor ; Michael D. Waters, technical editor
ContributionsWoodhead, Avril D, Waters, Michael D, United States. Environmental Protection Agency. Office of Research and Development
The Physical Object
Paginationxvii, 224 p. :
Number of Pages224
ID Numbers
Open LibraryOL17967142M

Download Short-term tests for environmentally induced chronic health effects


Abstract. Any credible assessment of the effects of low doses of radiation or chemicals on humans is difficult for several reasons (Setlow, ): 1) human data are almost always statistically inadequate with a few possible exceptions such as cigarette smoking and asbestos exposure (Peto, this volume), 2) extrapolation from experimental data on animals to predictions for exposed humans often Cited by: 1. The goals of toxicity testing are to identify possible adverse effects of exposure to environmental agents, to develop dose-response relationships that can elucidate the severity of effects associated with known exposures, and ultimately to predict the effects of exposure of human populations. Historically, the Health Effects Research Laboratory has made a strong commitment to the development and implementation of short-term tests for potential health effects of environmental agents. This commitment is evidenced by the formation within this laboratory of two new programs; the Genetic Toxicology Program and the Neurotoxicology Program. It is well documented that inhalation of sulfur mustard or Lewisite causes acute damage to the respiratory tract. In fact, pulmonary injury is the principal cause of mortality in the first few days to weeks after exposure to sufficiently high concentrations of sulfur mustard (Hosseini et al., ; Papirmeister et al., ; Willems, ).Cited by: 1.

  These evidences of recent alterations in human physiology support the idea that environmentally induced imbalances set the stage for cancer and other chronic diseases. Modern diets contain significantly higher levels of pro-inflammatory compounds in comparison to the anti-inflammatory nutrients common in the diets of early peoples (Simopoulos Cited by: 6. Many adverse health effects on humans have been reported in association with biomedical uses of GA, with % aqueous GA solution generally used for cold sterilization and GA exposure ranges of. J.E. Klaunig, L.M. Kamendulis, in Comprehensive Toxicology, In vivo gene mutation assays. In vivo genotoxicity tests are an important complement to in vitro mutagenicity tests. The in vivo tests have advantages over the in vitro test systems in that they take into account whole-animal processes such as absorption, tissue distribution, metabolism, and excretion of chemicals and. Abstract. The problems to be addressed in this paper and in this session are twofold: first, to identify and confirm mutagenic and presumptive carcinogenic chemicals through short-term tests (based on the use of plant as well as animal materials); and second, to determine the relationship of demonstrated effects in short-term tests to actual hazards and risks to human : Michael D. Waters.

Asthma, chronic obstructive pulmonary disease (COPD), and moderate to severe byssinosis require chronic treatment to maintain pulmonary function. Drug therapy is not curative, with disease progression possibly continuing despite treatment. Environmentally-induced asthma and COPD are treated in a manner similar to asthma and COPD due to other. -HEalth psychologists have developed a variety of short term behavioral interventions to address health related problems, including managing pain, modifying bad health habits such as smoking, and managing the side effects of treatments -Techniques that take a few hours to teach can produce years of benefit. SDSes can be obtained from the manufacturer or employer, and some can be found on internet sites. Information about health effects related to these toxins can also be found by consulting other sources, such as poison control centers (in the United States, dial ), consultants, agencies, and useful references. Acrylamide in Food: Analysis, Content and Potential Health Effects provides the recent analytical methodologies for acrylamide detection, up-to-date information about its occurrence in various Author: Vural Gökmen.